Dr. Stephanie E. King

Dr. Stephanie E. King

Ph.D.

School of Medicine

Assistant Professor of Medical Genetics, Biostatistics and Epidemiology

Courses:

 Medical Genetics, Biostatistics and Epidemiology


Biography:


Stephanie E. King, Ph.D., has an extensive background in the ground-breaking fields of transgenerational epigenetics, environmental epigenetics, and Developmental Origins of Health and Disease (DOHaD). Her research investigates the transgenerational inheritance of disease following environmental exposures including toxicants and stressors. She received her doctorate with distinguished awards from Washington State University under one of the most well-established researchers in her field. She held an Alberta Innovates Postdoctoral Fellowship in Research Innovation at the University of Lethbridge Canadian Centre for Behavioural Neuroscience.

Her research has been published in several journals including Trends in Endocrinology and Metabolism, Developmental Biology, Adipocyte, Environmental Epigenetics, and Nature Scientific Reports. Her research was listed as one of the top 10 most downloaded papers for Scientific Reports in 2019 generating numerous news reports globally. She has also given programs for several scientific organizations including the Alberta MS Network, the Canadian National Perinatal Research Meeting, Developmental Origins of Health and Disease Canada, and the Society for the Study of Reproduction.

In addition to her research interests, Dr. King also produces scientific illustrations that have been featured in research articles and textbook chapters as well as textbook and journal covers. She intends to use her skills to create diagrams for her students that more easily explain complex concepts in the field of genetics.

 

Transgenerational Epigenetics

Epigenetic Regulation of Gene Expression

Reproductive Biology

Human Physiology

Cadaveric Anatomy

Endocrine Toxicology

International Day of Women and Girls in Science Feature, University of Lethbridge, 2021

Alberta Innovates Postdoctoral Fellowship in Health Innovation 2+1 Competition. Transgenerational Inheritance of Neuroinflammation: A Multi-omics Approach to Finding a Biomarker for Increased Susceptibility to Parkinson’s Disease, 2021


Research article: Assessment of Glyphosate Induced Epigenetic

Transgenerational Inheritance of Pathologies and Sperm Epimutations:

Generational Toxicology received 46,583 article downloads in 2019, placing it as one of the top 100 downloaded papers for Scientific Reports in 2019.

https://www.nature.com/collections/ceabbdbhhe


Fodor-Wells Outstanding Graduate Student Award, 2019


Herbert L. Eastlick Distinguished Graduate Fellowship, 2017-2019

American Association for the Advancement of Science Program for Excellence in Science award, 2018

King SE et al. (2021) Transgenerational prenatal stress induces altered epigenetic and transcriptomic changes in neurodevelopment and the maternal-fetal interface (in prep).


King SE et al. (2021) Transgenerational inheritance of aberrant neurodegenerative pathway gene expression detected in the placenta and fetal cortex (in prep)

King, SE, Skinner, MK. (2020) Epigenetic transgenerational inheritance of obesity susceptibility. Trends Endocrinol Metab. 31(7), 478–494.


Ben Maamar M, King SE, Nilsson E, Beck D, Skinner MK. (2020) Epigenetic transgenerational inheritance of parent-of-origin allelic transmission of outcross pathology and sperm epimutations. Developmental Biology 458 (1), 106-119.


King SE, Nilsson E, Beck D, Skinner MK. (2019) Adipocyte epigenetic alterations and potential therapeutic targets in transgenerationally inherited lean and obese phenotypes following ancestral exposures. Adipocyte 8 (1).


Kubsad D, Nilsson E, King SE, Sadler-Riggleman I, Beck D, Skinner MK. (2019) Assessment of glyphosate induced epigenetic transgenerational inheritance of pathologies and sperm epimutations: generational toxicology. Scientific Reports 9 (1), 1-17.


King SE, McBirney M, Beck D, Sadler-Riggleman I, Nilsson E, Skinner MK. (2019). Sperm epimutation biomarkers of obesity and pathologies following DDT induced epigenetic transgenerational inheritance of disease. Environmental epigenetics 5 (2), dvz008.


Nilsson E, King SE, McBirney M, Kubsad D, Pappalardo M, Beck D, Sadler-Riggleman I, Skinner MK (2018) Vinclozolin Induced Epigenetic Transgenerational Inheritance of Pathologies and Sperm Epimutation Biomarkers for Specific Diseases. Plos One 13(8):1-29, e0202662.


McBirney M*, King SE*, Pappalardo M, Houser E, Unkefer M, Nilsson E, Sadler Riggleman I, Beck D, Winchester P, Skinner MK (2017) Atrazine Induced Epigenetic Transgenerational Inheritance of Disease, Lean Phenotype and Sperm Epimutation Pathology Biomarkers. PLoS One. 12(9):e0184306

Environmental Epigenetics and Systems Biology of Increased Susceptibility to Obesity

Epigenetic Transgenerational Inheritance of Disease Following Ancestral Exposure to Environmental Insults

Identifying Potential Germline Biomarkers of Increased Susceptibility to Disease in Offspring

Epigenetic Molecular Disease Etiology of Disease

Health Disparities in Populations with Early Life or Ancestral Exposure to Environmental Insults

 

Alberta MS Network Local Highlights Seminar, 2021 - The Epigenetic Etiology of Neuroinflammation and Demyelination in Multiple Sclerosis


University of Lethbridge Neur 3640: Brain Plasticity Guest Lectures, 2020 - Genetic and epigenetic bases of plasticity


Alberta MS Network Summer Zoom Lecture Series, 2020 – lecture. Environmental Epigenetic Factors in Multiple Sclerosis


University of Lethbridge Genome Sciences Club, 2020. Transgenerational and Multigenerational Prenatal Stress Induces Altered Epigenetic Marks and Gene Expression in the Placenta and Fetal Cortex


Canadian National Perinatal Research Meeting, 2020

Transgenerational Prenatal Stress Induces Altered Epigenetic Marks and Expression in the Placenta and Fetal Cortex


Developmental Origins of Health and Disease Canada Meeting, 2020

Transgenerational Prenatal Stress Induces Altered Epigenetic Marks and Expression in the Placenta and Fetal Cortex

Washington State University School of Biological Science Seminar, 2019. The Epigenetic Transgenerational Inheritance of Obesity and Adult Onset Diseases


Washington State University School of Biological Sciences Graduate Student Symposium, 2019. The Epigenetic Molecular Etiology of Transgenerationally Increased Susceptibility to Obesity


Washington State University School of Biological Sciences Biolunch, October 2018. The Epigenetic Molecular Etiology of Transgenerationally Increased Susceptibility to Obesity


Center for Reproductive Biology Meeting, 2018. Sperm Epimutation Biomarkers of Obesity and Pathologies following DDT Induced Epigenetic Transgenerational Inheritance of Disease